- Sales & Marketing Consultant, Leadville
- Sand Gravel & Aggregate, Leadville
- Sandwich Shop Restaurants, Leadville
- Satellite TV Service, Leadville
- Schools For The Physically Challenged, Leadville
- Secondary Schools, Leadville
- Security Brokers & Dealers, Leadville
- Security Services, Leadville
- Senior Citizens Service & Health Organizations, Leadville
- Sewing & Yarn Stores & Supplies, Leadville
- Sewing Contractors, Leadville
- Sheriff's Department, Leadville
- Shopping & Shopping Services, Leadville
- Ski & Snowboard Instructions, Leadville
- Ski Centers, Leadville
- Ski Resorts, Leadville
- Ski Shops - Equipment & Supplies Sales & Rental, Leadville
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- Ski, Snowboard & Snowmobile Shop - Equipment Rental & Services, Leadville
- Snacks & Desserts, Leadville
- Snow Removal Services, Leadville - Snow Plow Service
- Snowmobile Dealers, Leadville - Parts, Gear, Clothing & Accessories
- Snowmobile Rentals & Leasing, Leadville
- Snowmobile Repair, Parts, Sales & Service, Leadville
- Social Services & Welfare, Leadville
- Special Education & Care, Leadville
- Specialty Animal Services, Leadville
- Specialty Stores, Leadville
- Spiritualists, Leadville
- Sporting Goods Stores, Leadville
- Staffing & Support Services, Leadville
- State Government, Leadville
- Steak House Restaurants, Leadville
- Support Services, Leadville
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